OK, I worked out a good system for using stops and marks for routing multiple domino-sized mortises, and it takes more time to unclamp an reclamp the new piece of wood than it takes to route the mortise!
I have to say, the Festool 8mm HSS spiral bit is sharp! After cutting 22 mortises with it in white pine, it can still puncture my finger with the tip of the spiral, and the cut is clean.
Eventually I'll get a Domino...but for now this is fun! although very limiting...but since I don't make a living doing this, who cares?
You can see that I made the mortise a bit wider (1-2mm) than the 8x22x40mm domino, I could have tightened it up a little.
I used the dominos in the 3/4" joints in the door, and made larger, deeper ones for the 5/4 frame.
Now I have to glue up the storm door, I'll post pics when I'm done.
Thanks for your input, everyone.