Jesse,
What is the advantage of using Domino joinery for a breadboard end if you are also doing the machining steps used in making a traditional breadboard end? Once you have formed the tongue (on the main table piece) and the groove (on the breadboard end), all that is left to do is to drill three holes for the dowel pins in the main table top and the breadboard, and elongate the holes near the two edges of the main table top to form slots to accomodate expansion and contraction due to moisture changes, then apply a little glue to only the center portion of the tongue and assemble. I intentionally offset the holes in the endpiece with the groove so that upon assembly and driving in the dowels, they pull the end piece up tight against the main table top having the tongue. (Similar to the technique used when pinning the beams together in old barn construction.) The only advantage I can see from additional use of the Domino would be to further reinforce the tongue by use of dominos that are longer than the integrally formed tongue, or saving a little precious wood of your main table top because you don't have to consume as much of its length to form the tongue. Am I misunderstanding something about your proposed use of dominos in making a breadboard end joint?
Dave R.