I tend to agree, even with the interface pad it will soften the live edge details. You can probably use it for part of the sanding depending on the specific slab. I finish smaller edge details using a Foredom with 3M radial disks.
A Dremel works with those disks also, but I have fallen in love with the Foredom in the shop.
RMW
Chris Wong said:
It depends on the look you're after. I would say that sanding a live edge changes the shape too much, no matter how soft of an interface pad you use.