I don't use anything just raw mdf. However, I put butcher paper down before a glue up since I clamp all my glue ups down to my table to hold them flat and than into a known square corner. I also own a 4' x 8' CNC so making new tops costs me $22.00 for the sheet of MDF. IF I were to make a table to last a long time I would do what a friend had done. He laminated melamine to the bottom bored the holes for the Mft top and than uses the raw side for cutting and the melamine side for glue ups. I will say I am still on my first 4' x 8' top that I nade over a year ago. I ruined the one side flipped it and still have another 6-8 months on this side.
If you want to put a finish of some kind on it though. I would use Renaissance wax and put it on with the Rotex.