I have been using Dominoes exclusively for all joining for about 2 years including case construction. I have a large amount of cases to build now and I am considering biscuits. Here is why. I visited a friends shop a couple of days ago that builds large frameless cases for kitchens and he uses only biscuits using a Lamello joiner. I commented that the units looked as though they needed temp. support across the backs while being transported to the job and he showed me how strong they were. I thought about it and there would be more surface area with the biscuits than the Dominoes. Only a 5 mm Domino can be used on 3/4" ply because when cutting a slot for a larger one it will come through the ply. However a #20 biscuit can be used on 3/4" with about 3 times the surface area than a 5 mm Domino. I have not used biscuits in about 5 years but for this application they seem like a better choice. I made samples of ply corners using both and the ply busted in both cases and not the tenon or biscuit. Any input for me because I start assembling the cases tomorrow.