With appropriate instruction, as provided by all three Festool Training Centers in the USA, using a vertical panel raising bit in an OF1400 on the CMS become easy and natural. I have done so in the Door and Drawer class in Henderson, NV with Steve Bace instructing.
In my own business virtually all of our panel raising is done on a large Felder tilting arbor shaper, because since the 1940s I have used shapers of one kind or another to raise panels. So has the master cabinet maker working for me who heads our frame and door department.
Besides raising panels there are several other woodworking operations done on router tables in which it is more efficient to run the work vertically against the fence. When I am instructing I encourage trainees to learn how and practice. What I discourage is an attitude that just because at first a particular method does not seem 'natural' means it is not a good method, perhaps for another woodworker.