For window frames I can see no problem but to rely on dominoes for say a front door I would be very sceptical. The stresses/enviromental changes that an exterior door may endure would require a more traditional approach. Dominoes or loose tenons rely on the glue bond in effect to survive the stresses they are under, while mortice and tenon joints generally have the wedges or draw bore pegged 'mechanical' back up. Just my viewpoint on the subject.
Rob.