The higher speed should give you better results.
However, looking at the Kreg bit, it appears that the wings of the bit aren't quite as steep as my other brad point bits. Which means the holes are never going to be as clean all other things being equal.
For new cabinet work with lots of system holes, I'd look at another jig/system. I only use this jig for adding a couple of holes to an already installed cabinet. Something which it excels at in my view, because of its small and compact size. I'd never use it for doing 4 rows of system holes on an entire cabinet, let alone a couple of dozen.