Jerry,
[welcome] to the forum. This topic could be hotly debated, but based on my memory one of our members - Eiji Fuller has built some bad to the bone entrance doors - 8+ feet tall using the Domino.
I would say a french door using domino tenons, and made with care, is the equal to a factory made door using dowels, and probably better. The important thing is the design, layout and quantity of the dominos.
Is it the equal of a door made with traditional wedged through-tenons? I say no, but I will not be the judge of that...time will be.