On the table saw it is just three setups. You could rip off a few lengths and then cut to length as needed.
Unless you have a powerful shaper and get a custom shaper blade, this is going to require more than one setup for the router too.
You will need one setup for the 45s and one for the center groove. If you make setup blocks for the saw, those will go quickly.
It does not look particularly challenging for the table saw. Not much more than making Shaker rails and stiles on the saw, which I do all the time. And with the rails and stiles the fit to the center panel has to be rather precise and the fit of the stub tenon to the groove has to be exact for both thickness and depth. I can't imagine the requirements for your profile will be much more demanding than that.