I dunno, I'd take that with a grain of salt.
As most of my material is reclaimed, I've pulled apart more furniture and doors than I can count, and I've never been able to cleanly pull apart things that had Domino tenons properly glued in without a lot of breakage.
Things constructed with dowels though I've always generally found far easier to disassemble even when glued, with very minimal damage as a result. Sometimes just simply "rocking" the joint is all that's required.
How many dowels though?
A proper application of dowels is with an industrial doweling machine, seeing a dowel every 32mm (the distance is not arbitrary, 20 mm is too close, 40 mm is needlessly far). I call this "full shebang dowelling" given how rare this is in the hobby space.
TLDR:
"Full shebang" dowels are an unquestionably strongest option for weak-core-strong-surface engineered materials. They are still good for hardwood and passable for softwood.
"Full shebang" dominoes, and flat floating tenons in general, are one of the strongest option for wood materials, they are passable for engineered materials, good-enough for non-load-bearing joints and most load-bearing ones yet will yield to dowels for maximum strength at a given joint length.
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Because the "proper" application of a dowel sees a dowel every 32mm. Basically what LR32 allows you. That makes for about 16-18 dowels connecting your average cabinet side to a bottom/top. It may sound overkill, but it is not. With weak engineered materials such is necessary to transfer the forces into the weak core of the board that is glue-able while the strong surface is glue-proof. Modern flat-packed furniture needs not apply. Even if glued on assembly.
I have broken down many of such properly made carcasses, our apartment was full of such stuff made in 1940s to 1980s . Beyond cutting through the dowels, or steam-freeing the piece which an engineered board carcass has no chance to survive itself, there is no way one can take such a carcass apart without major damage in the joint area. Nada.
A dowel is an industrial production technology and
done properly provides for the strongest joints *in engineered surface materials* like laminated chipboard or MDF that is possible with such materials. This is due to the physics of those materials having a weak core and strong surfaces. "Full shebang" dowels are still OK-ish but will cede to dominoes for softwood use. Softwood has no strong surface the dowel can use for leverage making the domino superior. This is important to understand as it can be only partially mitigated by using longer dowels.
Sure. You can use dominoes across the joint in a similar fashion. Yet, such joint will be weaker in chipboard with dominoes. With dowels the mortise takes less width allowing you to place *more* dowels in same length of a joint. Why this is important is that the dowel itself is not the weak point. The board core is. The unweakened part of it specifically. The more of the board you disturb by the wider dominoes, the weaker it becomes. That is what makes dowels the ultimate-strength floating tenon joint: You can use the most of them while disturbing the least of the stock with holes.
Now, you ask, why bother if a couple dominoes on the ends of the board will do? And THAT is exactly the point. DOMINO is *not* an industrial production tool, it is NOT meant to provide the strongest joint possible. Instead it is an artisan tool to provide a good-enough joint at minimal labour expenditure.
Above is why I wrote earlier that the idea of three dowels at one place is correct - for you
need as many of them to get a similar effect a single domino provides. DD40 has two which is enough for hardwood but is weaker than a single domino and fails in softwood or chipboard, necessitating at least two plunges on each sides, 8 dowels total, for a secure joint.
The CTM long jigs - Packard noted - or the LR32 approach I prefer - are designed to mimic the industrial dowel joint. The 17 dowels per joint joint. An overkill for most uses, yet essential for some - think a free-ended butt-jointed chipboard shelf.
That is why I know that when/if I get the DOMINO, I will keep my jig. Precisely to be able to make super-strong carcasses from low quality materials. I still love the DOMINO I had rented a couple times for what it is meant for: efficiently making artisanal hardwood furniture and engineered material carcasses that
do not rely on load-bearing joints for strength.
EDIT: rephrased a bit